Intel® Quartus® Prime Pro Edition User Guide: Third-party Synthesis
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2.8. Simulation and Formal Verification
If area and timing requirements are satisfied, use the files generated by the Intel® Quartus® Prime software to program or configure the Intel device. If your area or timing requirements are not met, you can change the constraints in the Synplify software or the Intel® Quartus® Prime software and rerun synthesis. Intel recommends that you provide timing constraints in the Synplify software and any placement constraints in the Intel® Quartus® Prime software. Repeat the process until area and timing requirements are met.
You can also use other options and techniques in the Intel® Quartus® Prime software to meet area and timing requirements, such as WYSIWYG Primitive Resynthesis, which can perform optimizations on your .vqm netlist within the Intel® Quartus® Prime software.