ID:251024 Assignments have been changed outside the Assignment Editor. Do you want to save the changes before reloading the assignments? If you save the changes, you may overwrite some or all of the external changes.

CAUSE: You edited assignments outside the Assignment Editor, for example, in the Settings dialog box, but you did not save the edits that you made in the Assignment Editor before making external changes. The Quartus Prime software is asking whether you want to save the changes made in the Assignment Editor, which may result in the Quartus Prime software overwriting some or all of the changes made outside of the Assignment Editor.

ACTION: Click Yes to save the edits that you made in the Assignment Editor prior to making the external edits, and to possibly overwrite some or all of the external changes. Otherwise, click No to ignore the edits that you made in the Assignment Editor before making the external changes.