Due to a problem in the Quartus® Prime Pro Edition Software v21.3, the TX simplex and RX simplex channel cannot be merged into the same physical transceiver channel when different parallel clock frequency is detected between the TX Simplex channel and RX Simplex channel.
The parallel clock frequency is derived as:
Parallel clock frequency = Data Rate / PMA Width
There will be an error during the Support-Logic Generation stages. The error only happens when you use the PMA clocking mode. The system phase-locked loop (PLL) clocking mode is not affected by this problem.
This problem is scheduled to be fixed in a future release of the Quartus® Prime Pro Edition Software.