Description
No, when you use EPCQ or EPCQA quad-serial configuration device for AS configuration, you cannot connect VCCIO of I/O bank 1 to 2.5 V in Cyclone® III, Cyclone® IV, or Intel® Cyclone® 10 LP device.
This is because the minimum VOH of the FPGA is insufficient for driving EPCQ or EPCQA input pins.
Resolution
Use 3.0 V or 3.3 V for Bank 1 VCCIO in Cyclone III, Cyclone IV, and Intel Cyclone 10 LP devices when AS configuration with EPCQ or EPCQA devices is used.