Yes, EPCQ256 and EPCQ512 configuration devices are supported to store configuration images for Cyclone® IV devices. These can be used in Active Serial x 1 programming mode.
For more information on how to migrate from an EPCS to an EPCQ device, refer to AN727: EPCS to EPCQ Migration Guideline.
Also, refer to this related article: Can I use the EPCQ256 configuration device for remote system upgrade (RSU) with Arria® II, Stratix® IV, Cyclone® IV FPGA, and older devices?