In System Configuration File (.isc) Definition
An IEEE 1532 Data File (with the extension .isc) used by any IEEE 1532 supported programming application to program compliant and compatible Intel and non-Intel devices.
You can create ISC Files by pointing to Create/Update,and then clicking Create Jam, JBC, SVF, or ISC File on the File menu.
You can also create ISC Files using the Files tab of the Configuration Device Options dialog box, or using the Programming Files page of the Device and Pin Options dialog box.